Procell Cytogenetic Reagents, Cytoclear Cytoplasm Remover

Cytoclear GGS-JL004
Cytoclear is a newly developed product (consisting of a mixture of protein detergents) which can quickly dissolve and remove persistent cytoplasm (mainly caused by inadequate hypotonic treatment) during the methanol:acetic acid fixation stage of the chromosome harvesting procedure. In particular, it dissolves the lipid and glycoprotein structure of which cytoplasm is mainly composed. Clumped metaphases that would normally be impossible to analyse can now be restored. Cytoclear is a useful tool in FISH hybridizations as it enables the probe to reach the target by removing barrier cytoplasm


Without Cytoclear	With Cytoclear
Archival fixed bone marrow preparations labelled with Cytocell XY Dual label FISH probe Image courtesy of Cytocell Technologies Ltd