Procell Cytogenetic Reagents, Chromosome Resolution Additive

Chromosome Resolution Additive GGS-JL003
A novel formulation which prevents chemical contraction and encourages chromosome elongation by loosening the bonding within the supercoiled intrachromosomal structure. Antagonistic to the supercontracting effects of colchicine exposure, CRA acts as a molecular wedge, causing the chromosome structure to elongate. CRA is specially developed for tissues resistant to existing prophase techniques, such as bone marrow and tumour samples. This product does not contain Ethidium Bromide or Thymidine. CRA does not induce chromosome breakage.


Without CRA	With CRA
Comparison of metaphases from the same AML cell line, one with CRA added prior to metaphase arrest